암포마이신

암포마이신
암포마이신 구조식 이미지
카스 번호:
1402-82-0
한글명:
암포마이신
동의어(한글):
암포마이신
상품명:
Amphomycin
동의어(영문):
amfamycin;Nsc267431;Amphomycin
CBNumber:
CB9938498
분자식:
C58H91N13O20
포뮬러 무게:
1290.43
MOL 파일:
1402-82-0.mol

암포마이신 속성

알파
D25 +7.5° (c = 1 at pH 6)
끓는 점
854.06°C (rough estimate)
밀도
1.0985 (rough estimate)
굴절률
1.6700 (estimate)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
색상
크리스탈

안전

독성 LD50 orl-mus: 500 mg/kg 85GDA2 4(1),317,80

암포마이신 C화학적 특성, 용도, 생산

용도

Amphomycin is a lipopeptide antibiotic produced by Streptomycetes and Actinoplanes, initially reported by researchers at Bristol-Myers in 1953 from Streptomyces canus. Amphomycin was marketed as a complex of closely related analogues in the 1950s and 1960s. Structure elucidation was not completed until 2000. Amphomycin is active against Gram positive bacteria, inhibiting peptidoglycan synthesis and blocking cell wall development. Amphomycin is closely related to a number of “lost” antibiotics, aspartocin, crystallomycin, glumamycin, friulimicin, laspartocin, tsushimycin and zaomycin. Interest in amphomycin was re-awakened with the discovery of friulimicin activity against antibiotic resistant strains.

Safety Profile

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion.Induces hemolysis. Active against gram-positive bacteria.Suggested as a topical agent for animal and plantinfections. When heated to decomposition it emits acridsmoke and

암포마이신 준비 용품 및 원자재

원자재

준비 용품


암포마이신 공급 업체

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