Tacrolimus suppliers
Tacrolimus
- CAS:
- 104987-11-3
- MF:
- C44H69NO12
- MW:
- 804.02
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Properties
- Melting point:
- 113-115°C
- Boiling point:
- 871.7±75.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- Flash point:
- 2℃
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO: >3 mg/mL
- form
- solid
- pka
- 9.97±0.70(Predicted)
- color
- white
- Water Solubility
- Freely soluble in DMSO or ethanol. Poorly soluble in water.Soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.
- BCS Class
- 2
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
- InChIKey
- QJJXYPPXXYFBGM-LFZNUXCKSA-N
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H301-H361f-H373
- Precautionary statements
- P202-P260-P264-P270-P280-P301+P310
- Hazard Codes
- T,Xi,Xn,F
- Risk Statements
- 25-36/37/38-36-20/21/22-11
- Safety Statements
- 45-36-26-36/37-16-60-20
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- KD4201200
- HazardClass
- 6.1
- HS Code
- 29349990
Use
FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system. Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and activates NF-κB through phosphorylation and degradation of IκBα.
467 supplier list of "Tacrolimus"
$0.00-0.00 / 1KG
- Product Name:Tacrolimus
- Products Intro:Purity: 99|Package: 1KG;0.00;USD|5KG;0.00;USD|25KG;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2023788-19-2,910463-68-2,2381089-83-2,1627580-64-6,13463-67-7
$50.00/ 1kg
- Product Name:Tacrolimus
- Products Intro:Purity: 0.99|Package: 1kg;50.00;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate