- 1-Boc-2-piperidone
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- $9.00 / 1KG
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2024-01-08
- CAS:85908-96-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000tons
- N-Boc-2-piperidone
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- $15.00 / 1KG
-
2021-08-12
- CAS:85908-96-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- N-Boc-2-piperidone
-
- $15.00 / 1KG
-
2021-07-13
- CAS:85908-96-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| N-Boc-2-piperidone Basic information |
| N-Boc-2-piperidone Chemical Properties |
Melting point | 29-36 °C | Boiling point | 110°C/0.1mmHg(lit.) | density | 1.099±0.06 g/cm3(Predicted) | Fp | >110 °C | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | solubility | Chloroform, Methanol | form | Solid | pka | -2.29±0.20(Predicted) | color | Off-White | BRN | 4674955 | InChI | InChI=1S/C10H17NO3/c1-10(2,3)14-9(13)11-7-5-4-6-8(11)12/h4-7H2,1-3H3 | InChIKey | ULMHMJAEGZPQRY-UHFFFAOYSA-N | SMILES | N1(C(OC(C)(C)C)=O)CCCCC1=O | CAS DataBase Reference | 85908-96-9(CAS DataBase Reference) |
Hazard Codes | N | Risk Statements | 50 | Safety Statements | 24/25-61 | RIDADR | UN 3082 | WGK Germany | 3 | HazardClass | IRRITANT | HS Code | 29337900 |
Provider | Language |
ALFA
| English |
| N-Boc-2-piperidone Usage And Synthesis |
Chemical Properties | Off-White Low Melting Solid | Uses | N-Boc-2-piperidone(85908-96-9) is used as a synthetic intermediate in the preparation of various biological inhibitors. | Preparation | 4-Benzensulfonylmethyl-4-hydroxy-piperidine TFA (B-1) Diisopropylethylamine (28.3 mL, 162.75 mmol) and di-t-butyl dicarbonate (28.4 g, 130.02 mmol) were added in sequence to a mixture of piperidone hydrate hydrochloride (12) (10.0 g, 65.1 mmol) in methanol (50 mL). The mixture was stirred at room temperature for 20 hours. After that, removed the solvent and the remaining was separated with ether and 1 M KHSO4 solution. The organic layer was washed with brine and saturated NaHCO3. Finally, N-Boc-2-piperidone was obtained after purification.
| Definition | ChEBI:N-Boc-2-piperidone-protected by t-Boc. It is also known as 1-N-Boc-2-piperidone,1-N-Boc-2-piperidone, or 1-(tert-Butoxycarbonyl)-2-piperidone.
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| N-Boc-2-piperidone Preparation Products And Raw materials |
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