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Rutamycin

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Rutamycin Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Rutamycin；A 272;A272;A-272;Oligomycin D
CAS:1404-59-7
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 15093356674;
Email: laboratory@coreychem.com
Products Intro: Product Name:Rutamycin
CAS:1404-59-7
Purity:98% Package:1KG;1.8USD
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:Oligomycin D
CAS:1404-59-7
Purity:>95% by HPLC Remarks:BOC Sciences also provides custom synthesis services for Oligomycin D.
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:Oligomycin D
CAS:1404-59-7
Purity:NLT 98% Remarks:MC521921
Company Name: Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Tel: +86-19164747840 +86-13119157289
Email: 13119157289@163.com
Products Intro: Product Name:Rutamycin
CAS:1404-59-7
Purity:>=0.98 Package:G/bottle; Kg/bag; 25kg/barrel Remarks:in stock Purity: 99% | Package: As Buyer's Request
Rutamycin Basic information
Product Name:Rutamycin
Synonyms:26-Demethyloligomycin A;A-272;RR-32705;RRNo-32705;RutaMycin, 26-deMethyloligoMycin A, A 272, RR 32705, RutaMycin A;Rutamycin;oligomycin D;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,29-octamethyl-,(1S,2'R,4E,5'S,6S,6'S,7S,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,29R)-
CAS:1404-59-7
MF:C44H72O11
MW:777.042
EINECS:
Product Categories:
Mol File:1404-59-7.mol
Rutamycin Structure
Rutamycin Chemical Properties
Melting point 116-119°
alpha D20 -62° (c = 1.36 in CHCl3)
Boiling point 883.4±65.0 °C(Predicted)
density 1.15±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A lyophilisate
pka12.52±0.70(Predicted)
Safety Information
RIDADR 2811
HazardClass 6.1(b)
PackingGroup III
ToxicityLD50 oral in mouse: 800mg/kg
MSDS Information
Rutamycin Usage And Synthesis
DescriptionOligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport. Oligomycin D is reported to inhibit K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM and is cytotoxic to SW620 colon cancer cells with an IC50 value of 36 μM.
UsesOligomycin D is an inhibitor of mitochondrial F1F0-ATPase.
UsesOligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.
Rutamycin Preparation Products And Raw materials
Tag:Rutamycin(1404-59-7) Related Product Information
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