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Product Name:N2-OH-PhIP CAS:124489-20-9 Purity:98% HPLC Package:100mg,250mg,1g
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| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Basic information |
Product Name: | 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine | Synonyms: | N-OH-PHIP;N-HYDROXY-2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE;N-HYDROXY-PHIP;1-Methyl-2-(hydroxyamino)-6-phenyl-1H-imidazo[4,5-b]pyridine;2-(Hydroxyamino)-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine;N-(1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridine-2-yl)hydroxyamine;N-(1-methyl-6-phenylimidazo[4,5-b]pyridin-2-yl)hydroxylamine;N2-OH-PhIP | CAS: | 124489-20-9 | MF: | C13H12N4O | MW: | 240.26 | EINECS: | | Product Categories: | | Mol File: | 124489-20-9.mol | |
| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Chemical Properties |
Boiling point | 421.7±55.0 °C(Predicted) | density | 1.35±0.1 g/cm3(Predicted) | pka | 11.70±0.40(Predicted) |
| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Usage And Synthesis |
Uses | 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine is a mutagenic metablite of PhIP. PhIP is the most abundant mutagenic heterocyclic amine in cooked foods. Studies have shown the activation of 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in the formation of PhIP adducts and 5-OH-PhIP. | Definition | ChEBI: N-hydroxy-PhIP is an imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP. It has a role as a carcinogenic agent, a mutagen, a genotoxin, a human xenobiotic metabolite, a mouse metabolite, a rat metabolite and a neurotoxin. It is an imidazopyridine and a hydroxylamine. It is functionally related to a PhIP. |
| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine Preparation Products And Raw materials |
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