pederin

pederin Basic information
Product Name:pederin
Synonyms:pederin;D-manno-Nonitol, 2,6-anhydro-3,5,7-trideoxy-1-C-[[(2S)-2-hydroxy-2-[(2R,5R,6R)-tetrahydro-2-methoxy-5,6-dimethyl-4-methylene-2H-pyran-2-yl]acetyl]amino]-5,5-dimethyl-1,8,9-tri-O-methyl-, (1S)-
CAS:27973-72-4
MF:C25H45NO9
MW:503.63
EINECS:
Product Categories:
Mol File:27973-72-4.mol
pederin Structure
pederin Chemical Properties
Melting point 112-112.5°
Safety Information
MSDS Information
pederin Usage And Synthesis
DefinitionChEBI: A polyketide and carboxamide produced by a (Pseudomonas) bacterial endosymbiont of certain rove beetles (genus Paederus). Pederin is the agent responsible for the vesicant effects (linear or Paederus dermatitis) when the beetle is crushed against the skin. It is a powerful inhibitor of protein biosynthesis and mitosis and a potent antitumour agent.
Enzyme inhibitorpederine and paederine, from the blister beetle Paederus fuscipes inhibits eukaryotic protein biosynthesis and mitosis, even at concentrations of 2–3 nM. 1. Carrasco, Battaner & Vazquez Meth. Enzymol. 30, 282. 2. Jiménez Trends Biochem. Sci
pederin Preparation Products And Raw materials
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pederin