| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:T 98475;7-[(2,6-Difluorophenyl)Methyl]-4,7-dihydro-2-[4-[(2-Methyl-1-oxopropyl)aMino]phenyl]-3-[[Methyl(phenylMethyl)aMino]Methyl]-4-oxo-thieno[2,3-b]pyridine-5-carboxylicacid1-Methylethylester
CAS:192887-28-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:T 98475
CAS:192887-28-8
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
|
| Company Name: |
United States Biological
|
| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:T 98475
CAS:192887-28-8
|
|
| | T 98475 Basic information |
| Product Name: | T 98475 | | Synonyms: | 3-[(BENZYL-METHYL-AMINO)-METHYL]-7-(2,6-DIFLUORO-BENZYL)-2-(4-ISOBUTYRYLAMINO-PHENYL)-4-OXO-4,7-DIHYDRO-THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID ISOPROPYL ESTER;7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID 1-METHYLETHYL ESTER;T 98475;THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID, 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-, 1-METHYLETHYL ESTER;THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID, 7-[(2,6-DIFLUOROPHENYL)METHYL]-4,7-DIHYDRO-2-[4-[(2-METHYL-1-OXOPROPYL)AMINO]PHENYL]-3-[[METHYL(PHENYLMETHYL)AMINO]METHYL]-4-OXO-, 1-METHYL | | CAS: | 192887-28-8 | | MF: | C37H37F2N3O4S | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 192887-28-8.mol |  |
| | T 98475 Chemical Properties |
| Melting point | 168-170 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) | | storage temp. | Desiccate at +4°C |
| | T 98475 Usage And Synthesis |
| Uses | T 98475 is a novel, potent and orally active nonpeptide antagonist of the LHRH receptor. | | Definition | ChEBI: 7-[(2,6-difluorophenyl)methyl]-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]-3-[[methyl-(phenylmethyl)amino]methyl]-4-oxo-5-thieno[2,3-b]pyridinecarboxylic acid propan-2-yl ester is a thienopyridine and an isopropyl ester. | | Biological Activity | Potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC 50 values are 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors respectively). Inhibits LH release in vitro (IC 50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys. |
| | T 98475 Preparation Products And Raw materials |
|