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Erythromycin ethylsuccinate

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Products Intro: Product Name:Erythromycin ethylsuccinate
CAS:1264-62-6
Purity:99% Package:25KG
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Products Intro: Product Name:Erythromycin Ethylsuccinate
CAS:1264-62-6
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CAS:1264-62-6
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Products Intro: Product Name:Erythromycin ethylsuccinate
CAS:1264-62-6
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Erythromycin ethylsuccinate Basic information
Product Name:Erythromycin ethylsuccinate
Synonyms:ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE);ERYTHROMYCIN 2'-(ETHYL SUCCINATE);ERYTHROMYCIN ETHYLSUCCINATE;erythrocinethylsuccinate;erythromycin,mono(ethylsuccinate);erythromycin,mono(ethylsuccinate)(ester);Succinic acid, monoester with erythromycin;Erythromycin 2''-[3-(ethoxycarbonyl)propionate]
CAS:1264-62-6
MF:C43H75NO16
MW:862.05
EINECS:215-033-8
Product Categories:ERYPED;Organics;Interferes with Protein SynthesisAntibiotics;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Macrolides;Mechanism of Action;Spectrum of Activity;1264-62-6
Mol File:1264-62-6.mol
Erythromycin ethylsuccinate Structure
Erythromycin ethylsuccinate Chemical Properties
Melting point 219-224 C
Boiling point 778.19°C (rough estimate)
density 1.1417 (rough estimate)
refractive index 1.5280 (estimate)
Fp >110°(230°F)
storage temp. Sealed in dry,Room Temperature
solubility ethanol: soluble50mg/mL
form solid
pka13.09±0.70(Predicted)
color white
Water Solubility Freely soluble in organic solvents, practically insoluble in water
Stability:Hygroscopic
CAS DataBase Reference1264-62-6
Safety Information
Hazard Codes Xn,Xi
Risk Statements 42/43-36/37/38
Safety Statements 36-26
WGK Germany 2
RTECS WM9800000
HS Code 29419000
Hazardous Substances Data1264-62-6(Hazardous Substances Data)
ToxicityLD50 oral in mouse: > 10gm/kg
MSDS Information
ProviderLanguage
Erythromycin ethylsuccinate English
SigmaAldrich English
Erythromycin ethylsuccinate Usage And Synthesis
Chemical PropertiesERYTHROMYCIN ETHYLSUCCINATE is crystals
UsesA broad spectrum antibiotic commonly targeting bacteria responsible for respiratory tract infections
Usesantibacterial
DefinitionChEBI: Erythromycin ethylsuccinate is a erythromycin derivative that is erythromycin A in which the hydroxy group at position 3R is substituted by a (4-ethoxy-4-oxobutanoyl)oxy group. It is used for the treatment of a wide variety of bacterial infections. It is a succinate ester, a cyclic ketone, an erythromycin derivative and an ethyl ester. It is functionally related to an erythromycin A.
Brand nameE-Mycin (Pharmacia & Upjohn); E.E.S. (Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin (Wyeth).
General DescriptionErythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2'-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether.
Erythromycin ethylsuccinate Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->Succinic anhydride-->Erythromycin
Tag:Erythromycin ethylsuccinate(1264-62-6) Related Product Information
Erythromycin Metroprolol succinate Succinic acid iron succinate ETHOSUXIMIDE Ethyl formate Disodium succinate Diethyl succinate METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL METHYL 3-HYDROXYUNDECANOATE (S)-3-Hydroxy Myristic Acid Glycerol 5-hydroxydecanoate ERYTHROMYCIN A DIHYDRATE 2-Methylbutyl 2-methylbutyrate 4-(Dimethylamino)tetrahydro-2H-pyran MONO-ETHYL SUCCINATE FEMA 3604 9-OXODECANOICACIDETHYLESTER