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4'-Hydroxyphenyl Carvedilol

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4'-Hydroxyphenyl Carvedilol Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
CAS:142227-49-4
Purity:0.99 Package:5KG;1KG Remarks:C24H26N2O5
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Carvedilol Impurity 12
CAS:142227-49-4
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Carvedilol metabolite 4-Hydroxyphenyl Carvedilol；4-Hydroxyphenyl Carvedilol;4-Hydroxycarvedilol
CAS:142227-49-4
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: CR Corporation Lomited
Tel:
Email: fred.wen@crcorporation.cn
Products Intro: Product Name:4'-Hydroxyphenyl Carvedilol
CAS:142227-49-4
Company Name: China National Standard Pharmaceutical Corporation Limited
Tel: +8615391658522
Email: overseasales@yongstandards.com
Products Intro: Product Name:Carvedilol Impurity 12
CAS:142227-49-4
Purity:0.95 Package:Vials
4'-Hydroxyphenyl Carvedilol Basic information
Product Name:4'-Hydroxyphenyl Carvedilol
Synonyms:(R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL;(S)-(-)-4'-HYDROXYPHENYL-CARVEDILOL;(R)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol;(R)-4-Hydroxycarvedilol;(R)-BM 140686;(R)-BM 14686;(S)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol;(S)-4-Hydroxycarvedilol
CAS:142227-49-4
MF:C24H26N2O5
MW:422.47
EINECS:
Product Categories:Metabolite;Aromatics;Heterocycles;Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:142227-49-4.mol
4'-Hydroxyphenyl Carvedilol Structure
4'-Hydroxyphenyl Carvedilol Chemical Properties
Melting point 163-165°C
Boiling point 702.0±60.0 °C(Predicted)
density 1.305±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka9.94±0.20(Predicted)
color White to Light Brown
Safety Information
HS Code 9999999999
MSDS Information
4'-Hydroxyphenyl Carvedilol Usage And Synthesis
Description4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.
Chemical PropertiesOff-White Solid
UsesA metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.
Uses4'-Hydroxyphenyl Carvedilol is an optically active metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.
UsesAn optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity.
DefinitionChEBI: 4'-Hydroxyphenyl Carvedilol is a member of carbazoles.
4'-Hydroxyphenyl Carvedilol Preparation Products And Raw materials
Tag:4'-Hydroxyphenyl Carvedilol(142227-49-4) Related Product Information
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