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| | GANGLIOSIDE GD1A DISODIUM SALT Basic information |
| Product Name: | GANGLIOSIDE GD1A DISODIUM SALT | | Synonyms: | disialoganglioside G(D1A) from bovine brain;disialoganglioside-gd1A from bovine*brain;DISIALOGANGLIOSIDE-GD1A CELL CULTURE*TES TED;ganglioside gd1a, disialo from bovine brain;GANGLIOSIDEGD1ADISODIUMSALT,BOVINEBRAIN;GANGLIOSIDEGD1ADISODIUMSALT,BOVINEBRAIN,CELLCULTUREGRADE;disialogangloside GD1a;Disialoganglioside GD1a from bovine brain,Ganglioside GD1a, disialo from bovine brain | | CAS: | 12707-58-3 | | MF: | C84H146N4Na2O39 | | MW: | 1882.04098 | | EINECS: | | | Product Categories: | | | Mol File: | 12707-58-3.mol |  |
| | GANGLIOSIDE GD1A DISODIUM SALT Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: soluble | | form | lyophilized powder | | BRN | 6228822 |
| | GANGLIOSIDE GD1A DISODIUM SALT Usage And Synthesis |
| Description | Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones. | | Chemical Properties | White powder | | Uses | Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome. | | General Description | Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose. |
| | GANGLIOSIDE GD1A DISODIUM SALT Preparation Products And Raw materials |
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