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BOC Sciences
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Product Name:Fosmidomycin
CAS:66508-53-0
Purity:95% Remarks:Fosmidomycin is produced by the strain of Streptomyces lavendulae 8006. Fosmidomycin has anti-gram-p
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| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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020-39119399 18927568969 |
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isunpharm@qq.com |
| Products Intro: |
Product Name:Fosmidomycin sodium salt hydrate
CAS:66508-53-0
Purity:95% (NMR) Package:5MG; 25MG; 100MG; 1G
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| Company Name: |
Suzhou Vosun Biotech Co.,Ltd
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0512-66569378-8002 66569378 |
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info@vosunchemical.com |
| Products Intro: |
Product Name:Fosmidomycin
CAS:66508-53-0
Purity:97% Package:50g/;25g/;10g/;5g/;1g/
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| Company Name: |
Riedel-de Haen AG
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800 558-9160 |
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| Products Intro: |
CAS:66508-53-0
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| | Fosmidomycin Basic information |
| Product Name: | Fosmidomycin | | Synonyms: | 3-(Formylhydroxyamino)propylphosphonic acid;3-Phosphono 1-(N-formylhydroxyamino)propane;Antibiotic FR-31705;10 Mg, 50 Mg, 100 Mg, 1g;(3-(N-hydroxyforMaMido)propyl)phosphonic acid;(3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt;Fosmidomycin sodium salt hydrate;Phosphonic acid, P-[3-(formylhydroxyamino)propyl]- | | CAS: | 66508-53-0 | | MF: | C4H10NO5P | | MW: | 183.1 | | EINECS: | | | Product Categories: | | | Mol File: | 66508-53-0.mol |  |
| | Fosmidomycin Chemical Properties |
| Melting point | 158-160° (dec); mp 160-166° (dec) (Hemmi) | | storage temp. | -20°C | | solubility | H2O: soluble20mg/mL, clear | | form | powder | | color | white to beige |
| WGK Germany | 3 | | Toxicity | LD50 in mice and rats (mg/kg): >11000 orally; ~8000 s.c. (Wiesner, 2003) |
| | Fosmidomycin Usage And Synthesis |
| Uses | Fosmidomycin sodium salt hydrate has been used as an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a study to determine monotropin carvacrol biosynthesis in Satureja khuzistanica plant. | | Definition | ChEBI: Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme i
the non-mevalonate pathway of isoprenoid biosynthesis. | | Biochem/physiol Actions | Fosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) (MEP synthase): an antimalarial compound. 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). |
| | Fosmidomycin Preparation Products And Raw materials |
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