| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:TautoMycetin;(1R*,2S*)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentaMethyl-5,14-dioxo-15,17-octadecadienyl2,5-dihydro-β-hydroxy-4-Methyl-2,5-dioxo-3-furanpropanoicacidester
CAS:119757-73-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | TAUTOMYCETIN SOLUTION Basic information |
| Product Name: | TAUTOMYCETIN SOLUTION | | Synonyms: | TAUTOMYCETIN SOLUTION;3-hydroxy-3-(4-methyl-2,5-dioxo-2,5-dihydro-furan-3-yl)propionic acid 16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxooctadeca-15,17-dienyl ester solution;(1R*,2S*)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadienyl2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-3-furanpropanoicacidester;(1R,2S,3R,6S,7S,10S,12R,15E,βR,3R)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadienyl 2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-3-furanpropanoic acid ester;3-Furanpropanoic acid, 2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-, (1R,2S,6S,7S,10S,12R,15E)-16-ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadien-1-yl ester, (βR)-;Tautomycetin (10mg/mL in DMSO)
DISCONTINUED | | CAS: | 119757-73-2 | | MF: | C33H50O10 | | MW: | 606.75 | | EINECS: | | | Product Categories: | | | Mol File: | 119757-73-2.mol |  |
| | TAUTOMYCETIN SOLUTION Chemical Properties |
| Boiling point | 763.7±60.0 °C(Predicted) | | density | 1.148±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO: 10 mg/mL | | form | Colourless liquid | | pka | 12.36±0.20(Predicted) | | color | colorless |
| | TAUTOMYCETIN SOLUTION Usage And Synthesis |
| Uses | Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells. Tautomycin is closely related to another anhydride containing polyketide PP inhibitor called Tautomycetin which, in addition to being useful as a lead for cancer drug discovery, also is a very potent immunosuppressor. | | Definition | ChEBI: Tautomycetin is a sesquiterpenoid. | | Biological Activity | Potent activated T cell-specific immunosuppressor. Selectively inhibits PP1 over PP2 with IC 50 values of 1.6 and 62 nM respectively. Active in vivo . |
| | TAUTOMYCETIN SOLUTION Preparation Products And Raw materials |
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