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1,5-ISOQUINOLINEDIOL

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1,5-ISOQUINOLINEDIOL Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Email: sales@capotchem.com
Products Intro: Product Name:Isoquinoline-1,5-diol
CAS:5154-02-9
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: Product Name:5-Hydroxyisoquinoline-1(2H)-one
CAS:5154-02-9
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-09460
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:1,5-isoquinolinediol
CAS:5154-02-9
Purity:99% Package:1kg
Company Name: Antai Fine Chemical Technology Co.,Limited
Tel: 18503026267
Email: info@antaichem.com
Products Intro: Product Name:1,5-Dihydroxyisoquinoline
CAS:5154-02-9
Purity:0.98 Package:1KG;5KG;25KG
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 0551-65418671
Email: sales@tnjchem.com
Products Intro: Product Name:5-hydroxyisoquinolin-1(2H)-one
CAS:5154-02-9

1,5-ISOQUINOLINEDIOL manufacturers

  • 1,5-Isoquinolinediol
  • 1,5-Isoquinolinediol pictures
  • $0.00 / 1KG
  • 2023-04-08
  • CAS:5154-02-9
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 30tons/month
1,5-ISOQUINOLINEDIOL Basic information
Product Name:1,5-ISOQUINOLINEDIOL
Synonyms:1,5-ISOQUINOLINEDIOL;1,5-DIHYDROXYISOQUINOLINE;5-HYDROXYISOCARBOSTYRIL;5-HYDROXY-1(2H)-ISOQUINOLINE;5-HYDROXY-1(2H)-ISOQUINOLINONE;1,5-ISOQUINOLINEDIOL(1,5-DIHYDROXYISOQUI NO-LINE);1,5-Dihydroxyisoquinoline, 5-Hydroxy-1(2H)-isoquinolinone, DiQ;5-Hydroxyisoquinoline-1(2H)-one
CAS:5154-02-9
MF:C9H7NO2
MW:161.16
EINECS:637-104-6
Product Categories:Aromatics;Inhibitors
Mol File:5154-02-9.mol
1,5-ISOQUINOLINEDIOL Structure
1,5-ISOQUINOLINEDIOL Chemical Properties
Melting point 270-275 °C
Boiling point 287.44°C (rough estimate)
density 1.2480 (rough estimate)
refractive index 1.5050 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO: >36 mg/mL
form solid
pka8.52±0.20(Predicted)
color off-white
CAS DataBase Reference5154-02-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HS Code 29337900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
1,5-ISOQUINOLINEDIOL Usage And Synthesis
DescriptionThe poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50 = 0.39 μM). It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
Chemical Propertieswhite to off-white solid
UsesReagent used in the preparation of PARP inhibitor.
Uses1,5-Isoquinolinediol can be used as a reagent in the preparation of PARP inhibitor.
DefinitionChEBI: An isoquinolinol that is isoquinoline in which the hydrogens at positions 1 and 5 are replaced by hydroxy groups.
General DescriptionA potent inhibitor of poly(ADP-ribose) polymerase (PARP; IC50 = 390 nM). Reported to partially block SNAP (CN 487910)- induced cell death in SH-SYSY human neuroblastoma cells.
Biochem/physiol ActionsCell permeable: yes
storage+4°C
1,5-ISOQUINOLINEDIOL Preparation Products And Raw materials
Preparation Productsethyl 2-[(1-oxo-1,2-dihydroisoquinolin-5-yl)oxy]propanoate
Tag:1,5-ISOQUINOLINEDIOL(5154-02-9) Related Product Information
1,5-ISOQUINOLINEDIOL 7-isoquinolinediol,1-((3,4-dihydroxyphenyl)methyl)-1,2,3,4-tetrahydro-h 1,2,3,4-TETRAHYDRO-1-METHYL-6,7-ISOQUINOLINEDIOL HYDROBROMIDE,1,2,3,4-Tetrahydro-1-methyl-6,7-Isoquinolinediol 1-[(3,4-Dihydroxyphenyl)methyl]-1,2,3,4-tetrahydro-2-methyl-6,7-isoquinolinediol 5-Hydroxyisoquinoline Isoquinoline Isocarbostyril 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE,1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE 98% 1-(3,4-Dihydroxybenzyl)-6,7-isoquinolinediol Tretoquinol (S)-1,2,3,4-tetrahydro-6,7-dihydroxy-1-(3,4,5-trimethoxybenzyl)isoquinolinium chloride 5-METHOXY-2H-ISOQUINOLIN-1-ONE 6,7-Isoquinolinediol, 1-propyl- (9CI) d-1-(3,4,5-Trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 6,7-Isoquinolinediol, 1-(1-methylethyl)- (9CI) 6,7-Isoquinolinediol, 1-[(1S)-1,2-dihydroxyethyl]-1,2,3,4-tetrahydro- (9CI) 3,4-Dihydro-6,7-isoquinolinediol. Tretoquinol hydrochloride