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| | LCL-161 Basic information |
| Product Name: | LCL-161 | | Synonyms: | LCL-161;N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide;(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide;(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl);N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide;(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide LCL 161;LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins;CS-987 | | CAS: | 1005342-46-0 | | MF: | C26H33FN4O3S | | MW: | 500.63 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1005342-46-0.mol |  |
| | LCL-161 Chemical Properties |
| Boiling point | 713.7±60.0 °C(Predicted) | | density | 1.245±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | ≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH | | form | solid | | pka | 14.25±0.46(Predicted) |
| RIDADR | 3077 | | HS Code | 29341000 |
| | LCL-161 Usage And Synthesis |
| Description | LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins. | | Uses | LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs. |
| | LCL-161 Preparation Products And Raw materials |
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