- BENFLUOREX HYDROCHLORIDE
-
- $10.00 / 1KG
-
2021-08-31
- CAS:23642-66-2
- Min. Order: 1KG
- Purity: 99.99%
- Supply Ability: 20 tons/month
|
| | BENFLUOREX HYDROCHLORIDE Basic information |
| Product Name: | BENFLUOREX HYDROCHLORIDE | | Synonyms: | 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-ethanobenzoate(est;2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-ethanobenzoate(est;mediator;BENFLUOREX HYDROCHLORIDE;2-[[1-METHYL-2-[3-(TRIFLUOROMETHYL)-PHENYL]ETHYL]AMINO]ETHANOL BENZOATE (ESTER) HCL;2-[[1-METHYL-2[3-(TRIFLUOROMETHYL)-PHENYL]ETHYL]AMINO]ETHANOL BENZOATE ESTER HYDROCHLORIDE;2-((1-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]ETHYL)AMINO)ETHYL BENZOATE HYDROCHLORIDE;LABOTEST-BB LT00134683 | | CAS: | 23642-66-2 | | MF: | C19H21ClF3NO2 | | MW: | 387.82 | | EINECS: | 245-801-8 | | Product Categories: | Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 23642-66-2.mol |  |
| | BENFLUOREX HYDROCHLORIDE Chemical Properties |
| Melting point | 158-159?C | | storage temp. | Refrigerator | | solubility | Chlorform (Slightly), Methanol (Slightly), Water (Slightly) | | color | White |
| Hazard Codes | Xi | | WGK Germany | 2 | | RTECS | KL8275000 | | Hazard Note | Irritant | | HS Code | 2916399090 | | Toxicity | LD50 intraperitoneal in mouse: 108mg/kg |
| | BENFLUOREX HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | White Solid | | Originator | Mediator,Servier,France,1976 | | Uses | Hypolipedimic;Increase of glucose penetration and use by cells | | Uses | BENFLUOREX HYDROCHLORIDE can be used as an antihyperlipoproteinemic therapeutic and increase of glucose penetration and use by cells. | | Manufacturing Process | To a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β-
hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were
added successively 15 parts of 4.7N hydrochloric ether and a solution of 14
parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition
required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from
230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)-
2-(β-benzoyloxyethyl)amino propane hydrochloride
melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts
ether are added, then 10 parts of a concentrated solution of ammonium
hydroxide. The mixture is stirred a few minutes until the salt is dissolved,
then the ethered solution is poured off and dried. After the ether is
eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β-
benzoyloxyethyl)amino propane are obtained; the base is a colorless oil. | | Therapeutic Function | Antihyperlipidemic, Cardiovascular |
| | BENFLUOREX HYDROCHLORIDE Preparation Products And Raw materials |
|