Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
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3bsc@sina.com |
Products Intro: |
Product Name:L-759,633;(6aR,10aR)-3-(1,1-DiMethylheptyl)-6a,7,10,10a-tetrahydro-1-Methoxy-6,6,9-triMethyl-6H-dibenzo[b,d]pyran CAS:174627-50-0 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:L-759,633 CAS:174627-50-0 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:L-759,633 CAS:174627-50-0 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| L-759,633 Basic information |
Product Name: | L-759,633 | Synonyms: | L-759,633;(6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran;(6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene;6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)-;L 759;L-759;L759633,L-759633 | CAS: | 174627-50-0 | MF: | C26H40O2 | MW: | 384.59 | EINECS: | | Product Categories: | Cannabinoid receptor | Mol File: | 174627-50-0.mol | |
| L-759,633 Chemical Properties |
Boiling point | 447.9±45.0 °C(Predicted) | density | 0.956±0.06 g/cm3(Predicted) | storage temp. | Store at +4°C | solubility | Ethanol:20.0(Max Conc. mg/mL);52.0(Max Conc. mM) PBS (pH 7.2):0.25(Max Conc. mg/mL);0.65(Max Conc. mM) |
| L-759,633 Usage And Synthesis |
Description | L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of 8.1 nM and 10 μM, respectively. | Uses | L 759633 is a cannabinoid receptor (CB2) selective agonist and a structural analogues of ??9-Tetrahydro Cannabinol, an active constituent of cannabis. L 759633 has analgesic and anti-inflammatory properties. | Definition | ChEBI: 6h-dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6ar,10ar)- is a 1-benzopyran. | Biological Activity | High affinity, selective CB 2 receptor agonist (K i values are 6.4 and 1043 nM for CB 2 and CB 1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB 2 receptors expressed in CHO cells (EC 50 = 8.1 nM). |
| L-759,633 Preparation Products And Raw materials |
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