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| | Fananserin Basic information |
| Product Name: | Fananserin | | Synonyms: | 2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide;RP-62203;2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide;Fananserin;2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide;2-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide;Fananserin,Inhibitor,5-HT Receptor,inhibit,5-HT2,RP62203,RP-62203,dopamine,Dopamine Receptor,Serotonin Receptor,5-hydroxytryptamine Receptor | | CAS: | 127625-29-0 | | MF: | C23H24FN3O2S | | MW: | 425.52 | | EINECS: | | | Product Categories: | | | Mol File: | 127625-29-0.mol |  |
| | Fananserin Chemical Properties |
| Melting point | 95-97 °C(Solv: acetonitrile (75-05-8)) | | Boiling point | 641.1±65.0 °C(Predicted) | | density | 1.331±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Soluble to 100 mM in DMSO | | form | Powder | | pka | 7.31±0.10(Predicted) |
| | Fananserin Usage And Synthesis |
| Uses | Antipsychotic. | | Uses | Fananserin is an antagonist of 5-HT2A. | | Definition | ChEBI: LSM-2183 is a sulfonic acid derivative and a member of naphthalenes. | | Biological Activity | 5-HT 2A receptor antagonist that also displays high affinity at D 4 receptors (K i values are 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT 2A , D 4 , H 1 , α 1 , 5-HT 1A and D 2 receptors respectively). Inhibits inositol phosphate formation evoked by 5-HT in vitro (IC 50 = 7.76 nM) and antagonizes mescaline-induced head twitches in vivo . |
| | Fananserin Preparation Products And Raw materials |
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