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| | 1-butylbiguanide Basic information |
| | 1-butylbiguanide Chemical Properties |
| Melting point | 174-176 °C | | Boiling point | 271.89°C (rough estimate) | | density | 1.0291 (rough estimate) | | refractive index | 1.8070 (estimate) | | pka | 12.27±0.10(Predicted) |
| | 1-butylbiguanide Usage And Synthesis |
| Uses | Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase | | Definition | ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide. | | Brand name | Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine. | | World Health Organization (WHO) | Buformin is an analogue of phenformin. See WHO comment for
phenformin.
(Reference: (WHODI) WHO Drug Information, 2, 4, 1977) |
| | 1-butylbiguanide Preparation Products And Raw materials |
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