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| | Azidoacetic acid methyl ester Basic information |
| Product Name: | Azidoacetic acid methyl ester | | Synonyms: | Azidoacetic acid methyl ester;2-Azido-acetic acid Methyl ester;Acetic acid, 2-azido-, Methyl ester;Methyl 2-azidoacetate 97%;Methyl 2-azidoacetate - M3461;methyl 3-diazo-3-azaprop-3-enoate | | CAS: | 1816-92-8 | | MF: | C3H5N3O2 | | MW: | 115.0907 | | EINECS: | | | Product Categories: | | | Mol File: | 1816-92-8.mol |  |
| | Azidoacetic acid methyl ester Chemical Properties |
| Boiling point | 35 °C | | density | 1.182 g/mL at 25 °C | | refractive index | n20/D1.440 | | Fp | 48℃ |
| Hazard Codes | Xi | | Risk Statements | 5-10-36/37/38 | | Safety Statements | 26 | | RIDADR | UN 1993C 3 / PGIII | | WGK Germany | 3 |
| | Azidoacetic acid methyl ester Usage And Synthesis |
| Uses | - Methyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.
- It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.
- It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.
- Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.
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| | Azidoacetic acid methyl ester Preparation Products And Raw materials |
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