- friedelin
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- $0.00 / 1kg
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2023-10-12
- CAS:559-74-0
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20tons
- Friedelin
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- $0.00 / 5mg
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2023-02-24
- CAS:559-74-0
- Min. Order: 5mg
- Purity: ≥95%(HPLC)
- Supply Ability: 10 g
- FRIEDELIN
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- $1.00 / 1KG
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2019-07-14
- CAS:559-74-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 25kg
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| | FRIEDELIN Basic information |
| Product Name: | FRIEDELIN | | Synonyms: | FRIEDELIN;DA-FRIEDOOLEANAN-3-ONE;FRIEDELIN, TECH.;FRIEDELIN hplc;FRIEDELIN WITH HPLC;DA-friedooleanan-3-one, Friedelan-3-one;D:A-Friedooleanan-3-one (van) (8ci)(9ci);Einecs 209-205-1 | | CAS: | 559-74-0 | | MF: | C30H50O | | MW: | 426.72 | | EINECS: | 209-205-1 | | Product Categories: | Tri-Terpenoids | | Mol File: | 559-74-0.mol |  |
| | FRIEDELIN Chemical Properties |
| Melting point | 262-265 °C (lit.) | | alpha | D -27.8° (chloroform) | | Boiling point | 477.2±13.0 °C(Predicted) | | density | 0.963±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | color | White to Off-White | | Merck | 13,4293 | | BRN | 1916451 | | LogP | 10.287 (est) |
| | FRIEDELIN Usage And Synthesis |
| Uses | Friedelin is a flavonoid extract which displays radical scavenging and anti-typhoid activity. | | Uses | Friedelin can be used as a starting material in the synthesis of:
- Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
- Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
- Its 1,4-pyrazine derivatives as potent antimicrobial agents.
| | Definition | ChEBI: Friedelin is a pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork. It has a role as an anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and a plant metabolite. It is a pentacyclic triterpenoid and a cyclic terpene ketone. | | General Description | Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia?avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor?(H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent. |
| | FRIEDELIN Preparation Products And Raw materials |
| Raw materials | 6β,27-Dihydroxy-D:A-friedooleanan-3-one-->6β-Hydroxy-D:A-friedooleanan-3-one-->Kokoonol-->21-hydroxyfriedelan-3-one-->24,25,26-Trinoroleanan-3-one, 5,9,13-trimethyl-, (4α,5β,8α,9β,10α,13α,14β)--->3,4-Seco-3,4-epoxyfriedelane-3-one | | Preparation Products | D:A-Friedoolean-3-ene |
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