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4-CHLORO-2-NITROPHENOL

4-CHLORO-2-NITROPHENOL Basic information
Description Sources
Product Name:4-CHLORO-2-NITROPHENOL
Synonyms:O-NITRO-P-CHLOROPHENOL;4-chloro-2-nitro-pheno;AKOS BBS-00004667;4-CHLORO-2-NITROPHENOL;1-CHLORO-4-HYDROXY-3-NITROBENZENE;2-NITRO-4-CHLOROPHENOL;o-nitro-p-chorophenol;4-Chloro-2-nitrophenol,98%,containsuptoca10%water
CAS:89-64-5
MF:C6H4ClNO3
MW:173.55
EINECS:201-927-5
Product Categories:Dyestuff Intermediates;Organic Building Blocks;Oxygen Compounds;Phenols;Aromatic Phenols;Phenoles and thiophenoles;Intermediates of Dyes and Pigments
Mol File:89-64-5.mol
4-CHLORO-2-NITROPHENOL Structure
4-CHLORO-2-NITROPHENOL Chemical Properties
Melting point 85-87 °C(lit.)
Boiling point 242.5±20.0 °C(Predicted)
density 1.4914 (rough estimate)
refractive index 1.5810 (estimate)
solubility dioxane: soluble0.5g/5mL, clear, faintly yellow to yellow
pkapK1: 6.48 (25°C)
form powder to crystal
color Light yellow to Yellow to Orange
BRN 2048031
CAS DataBase Reference89-64-5(CAS DataBase Reference)
EPA Substance Registry System4-Chloro-2-nitrophenol (89-64-5)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-36-36/37/39
RIDADR 2811
WGK Germany 3
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29089990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
4-CHLORO-2-NITROPHENOL Usage And Synthesis
Description4-Chloro-2-nitrophenol, is a kind of chloronitrophenols (CNPs), being widely used in the synthesis of dyes, drugs and pesticides. Furthermore, it can be used to produce 2-Amino-4-chloro-phenol.It has become a major group of environmental pollutants. 4-Chloro-2-nitrophenol has been detected in various industrial effluents. Therefore, it has also been used as a model compound for evaluation of biodegradation strategy using microbes.
Sourceshttps://microbialcellfactories.biomedcentral.com/articles/10.1186/1475-2859-11-150
https://www.sciencedirect.com/science/article/pii/S0304389407009570
https://www.lookchem.com/4-Chloro-2-nitrophenol/
Chemical Propertiesyellow powder
UsesReduction of 4-Chloro-2-nitrophenol gives 2-amino-4- chlorophenol [95-85-2], and chlorination yields 2,4-dichloro-6-nitrophenol [609-89-2], which is reduced to 2-amino-4,6-dichlorophenol [527-62-8]. These substituted aminophenols are members of a large class of diazo components used for hydroxyazo dyes, which are important for wool and polyamide when converted to their chromium complexes. For the amine derived from the methyl ether of 4-Chloro-2-nitrophenol, 4- chloro-o-anisidine [93-50-5], the preferred route is methoxylation of 2,5-dichloronitrobenzene followed by reduction. 2-amino-4-chlorophenol reacts with phosgene to give 5- chlorobenzoxolinone which nitrates to the 6-nitro compound; the latter undergoes alkaline hydrolysis to 2-amino-4- chloro-5-nitrophenol.
Production Methods2,5-Dichloronitrobenzene is hydrolyzed with 8 % aqueous sodium hydroxide at 120 – 130 ℃ under pressure.
Tag:4-CHLORO-2-NITROPHENOL(89-64-5) Related Product Information
2,4-Dichloro-6-nitrophenol 4-CHLORO-2,6-DINITROPHENOL 4-Chloro-2-nitroanisole 4-CHLORO-2-NITROPHENOL 2,4-Dichloro-3-ethyl-6-nitrophenol Benzoic acid,5-chloro-2-hydroxy-3-nitro- 2-amino-4-chloro-6-nitrophenol monohydrochloride ,2-Amino-4-chloro-6-nitrophenol hydrochloride 4-CHLORO-6-NITRO-M-CRESOL 3-CHLORO-2,6-DIMETHOXY-5-NITROBENZOIC ACID 2-AMINO-4-CHLORO-6-NITROPHENOL 4-Chloro-1-(4-chlorophenoxy)-2-nitrobenzene 2,4-Dichloro-3-methyl-6-nitrophenol 3,4,6-TRICHLORO-2-NITROPHENOL 5-chloro-2-nitrophenol 2-(4-CHLOROPHENOXY)NICOTINIC ACID 2,6-Dichloro-4-nitrophenol 4-CHLORO-3-NITROPHENOL,4-Chloro-3-Nitrophenol98%,4-CHLORO-3-NITROPHENOL 98% 2,4-Dichloro-5-nitrophenol