GSK 2334470
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- $76 - $1060
- Product name: GSK 2334470
- CAS: 1227911-45-6
- MF: C25H34N8O
- MW: 462.59
- EINECS:
- MDL Number:MFCD21608525
- Synonyms:GSK 2334470;1S,4R)-3-(6-(3-aMino-1H-indazol-6-yl)-2-(MethylaMino)pyriMidin-4-yl)-N-cyclohexyl-4-MethylcyclohexanecarboxaMide;(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide;3-Piperidinecarboxamide, 1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-, (3S,6R)-;(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide GSK 2334470;GSK2334470;GSK 2334470;GSK-2334470;((3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-6-methylpiperidin-3-yl)(piperidin-1-yl)methanone;1S,4R)-3-(6-(3-AMINO-1H-INDAZOL-6-YL)-2-(METHYLAMINO)PYRIMIDIN-4-YL)-N-CYCLOHEXYL-4-METHYLCYCLOHEXAN
26 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 2x5mg
- 10mg
- 50mg
- 50
- 25mg
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number2445AH
- Product descriptionGSK2334470
- Packaging100mg
- Price$848
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2174
- Product descriptionGSK2334470
- Packaging10mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2174
- Product descriptionGSK2334470
- Packaging10mM(in 1mL DMSO)
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2174
- Product descriptionGSK2334470
- Packaging25mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2174
- Product descriptionGSK2334470
- Packaging50mg
- Price$329
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60273
- Product descriptionGSK2334470
- Packaging10mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1929
- Product descriptionGSK2334470 99%
- Packaging2x5mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18095
- Product descriptionGSK2334470 ≥98%
- Packaging5mg
- Price$76
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18095
- Product descriptionGSK2334470 ≥98%
- Packaging10mg
- Price$142
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18095
- Product descriptionGSK2334470 ≥98%
- Packaging25mg
- Price$335
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18095
- Product descriptionGSK2334470 ≥98%
- Packaging50mg
- Price$556
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM150829
- Product description(3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-methylpiperidine-3-carboxamide 98%
- Packaging100mg
- Price$583
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0917
- Product descriptionGSK2334470 99.91%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0917
- Product descriptionGSK2334470 99.91%
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0917
- Product descriptionGSK2334470 99.91%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004199
- Product descriptionGSK2334470 98+%
- Packaging50mg
- Price$358
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2445AH | GSK2334470 | 100mg | $848 | 2021-12-16 | Buy |
| ApexBio Technology | B2174 | GSK2334470 | 10mg | $105 | 2021-12-16 | Buy |
| ApexBio Technology | B2174 | GSK2334470 | 10mM(in 1mL DMSO) | $130 | 2021-12-16 | Buy |
| ApexBio Technology | B2174 | GSK2334470 | 25mg | $210 | 2021-12-16 | Buy |
| ApexBio Technology | B2174 | GSK2334470 | 50mg | $329 | 2021-12-16 | Buy |
| Arctom | CFN60273 | GSK2334470 | 10mg | $208 | 2021-12-16 | Buy |
| Axon Medchem | Axon1929 | GSK2334470 99% | 2x5mg | $154 | 2021-12-16 | Buy |
| Cayman Chemical | 18095 | GSK2334470 ≥98% | 5mg | $76 | 2024-03-01 | Buy |
| Cayman Chemical | 18095 | GSK2334470 ≥98% | 10mg | $142 | 2024-03-01 | Buy |
| Cayman Chemical | 18095 | GSK2334470 ≥98% | 25mg | $335 | 2024-03-01 | Buy |
| Cayman Chemical | 18095 | GSK2334470 ≥98% | 50mg | $556 | 2024-03-01 | Buy |
| Chemenu | CM150829 | (3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-methylpiperidine-3-carboxamide 98% | 100mg | $583 | 2021-12-16 | Buy |
| ChemScene | CS-0917 | GSK2334470 99.91% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0917 | GSK2334470 99.91% | 50mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0917 | GSK2334470 99.91% | 100mg | $500 | 2021-12-16 | Buy |
| Crysdot | CD31004199 | GSK2334470 98+% | 50mg | $358 | 2021-12-16 | Buy |
Properties
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :12.84±0.40(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :12.84±0.40(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that plays an important role in growth factor signaling by phosphorylating and activating a group of kinases, including protein kinase (PK)B, PKA, and certain isoforms of PKC. GSK2334470 is an inhibitor of PDK1 (IC50 = ~10 nM) that even at 100-fold higher concentrations does not affect the activity of 93 other protein kinases, including that of 13 closely related AGC kinase family members. In HEK293 cells, 30 nM - 1 μM GSK2334470 suppresses T-loop phosphorylation and activation of SGK, S6K1, and RSK, as well as the activation of Akt.Related product price
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