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ChemicalBook >> CAS DataBase List >> GSK484

GSK484

GSK484 price.
  • $37 - $3200
  • Product name: GSK484
  • CAS: 1652591-81-5
  • MF: C27H32ClN5O3
  • MW: 510.04
  • EINECS:
  • MDL Number:
  • Synonyms:GSK484;GSK484 (hydrochloride);CS-2265;PAD4 inhibitor GS484;GSK484 HCl;((3S,4R)-3-amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride;AOB6992;GTPL8577
Price21 Properties Safety Information Description
21 prices
Selected condition：
Brand
  • AK Scientific
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5686
  • Product descriptionGSK484
  • Packaging100mg
  • Price$2663
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging5mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging25mg
  • Price$718
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17488
  • Product descriptionGSK484 (hydrochloride) ≥95%
  • Packaging500μg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17488
  • Product descriptionGSK484 (hydrochloride) ≥95%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17488
  • Product descriptionGSK484 (hydrochloride) ≥95%
  • Packaging5mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17488
  • Product descriptionGSK484 (hydrochloride) ≥95%
  • Packaging10mg
  • Price$494
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019653
  • Product descriptionGSK484(hydrochloride) 98.00%
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019653
  • Product descriptionGSK484(hydrochloride) 98.00%
  • Packaging100mg
  • Price$1700
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004958
  • Product descriptionGSK484 97%
  • Packaging1mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004958
  • Product descriptionGSK484 97%
  • Packaging5mg
  • Price$146
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004958
  • Product descriptionGSK484 97%
  • Packaging10mg
  • Price$223
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004958
  • Product descriptionGSK484 97%
  • Packaging25mg
  • Price$553
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004958
  • Product descriptionGSK484 97%
  • Packaging50mg
  • Price$970
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004958
  • Product descriptionGSK484 97%
  • Packaging100mg
  • Price$1666
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5686 GSK484 100mg $2663 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 5mg $254 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 10mg $370 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 25mg $718 2021-12-16 Buy
Cayman Chemical 17488 GSK484 (hydrochloride) ≥95% 500μg $37 2024-03-01 Buy
Cayman Chemical 17488 GSK484 (hydrochloride) ≥95% 1mg $68 2024-03-01 Buy
Cayman Chemical 17488 GSK484 (hydrochloride) ≥95% 5mg $283 2024-03-01 Buy
Cayman Chemical 17488 GSK484 (hydrochloride) ≥95% 10mg $494 2024-03-01 Buy
ChemScene CS-0019653 GSK484(hydrochloride) 98.00% 5mg $190 2021-12-16 Buy
ChemScene CS-0019653 GSK484(hydrochloride) 98.00% 100mg $1700 2021-12-16 Buy
Crysdot CD31004958 GSK484 97% 1mg $53 2021-12-16 Buy
Crysdot CD31004958 GSK484 97% 5mg $146 2021-12-16 Buy
Crysdot CD31004958 GSK484 97% 10mg $223 2021-12-16 Buy
Crysdot CD31004958 GSK484 97% 25mg $553 2021-12-16 Buy
Crysdot CD31004958 GSK484 97% 50mg $970 2021-12-16 Buy
Crysdot CD31004958 GSK484 97% 100mg $1666 2021-12-16 Buy
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Properties

storage temp. :2-8°C
solubility :DMSO:25.0(Max Conc. mg/mL);49.01(Max Conc. mM)
Ethanol:25.0(Max Conc. mg/mL);49.01(Max Conc. mM)
PBS buffer (pH 7.2):5.0(Max Conc. mg/mL);9.8(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);58.82(Max Conc. mM) form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GSK484 is a reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme. It is selective for PAD4 over PAD1-3. GSK484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils. It exhibits favorable pharmacokinetic profiles in mouse and rat. See the Structural Genomics Consortium (SGC) website for more information.

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6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide GSK481 GSK461364 GSK583 1346572-63-1 RET Kinase inhibitor 1 864082-47-3 GSK2636771 GSK2982772 GSK 2334470 GSK J4 HCl GSK864 1346574-57-9 188591-46-0 GSK2837808A GSK-2256098 942206-85-1 GSK 2033 GSK6853

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Suppliers and manufacturers

Hubei Chuchang Biotech Co., Ltd.
GSK484 (hydrochloride)
$0.00 /500mg
GSK484 (hydrochloride) CAS:1652591-81-5
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