| Identification | Back Directory | [Name]
Benzamide, 4-[(9-cyclopentyl-6,7,8,9-tetrahydro-5,8-dimethyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)- | [CAS]
1001343-34-5 | [Synonyms]
Benzamide, 4-[(9-cyclopentyl-6,7,8,9-tetrahydro-5,8-dimethyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)- | [Molecular Formula]
C28H39N7O3 | [MOL File]
1001343-34-5.mol | [Molecular Weight]
521.65 |
| Hazard Information | Back Directory | [Uses]
PLK1-IN-5 is a potent PLK1 inhibitor with an IC50 of < 500 nM. PLK1-IN-5 shows anticancer effects (WO2008113711A1; compound I-4)[1]. | [Definition]
ChEBI: 4-[(9-cyclopentyl-5,8-dimethyl-6-oxo-7,8-dihydropyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)benzamide is a pyrimidodiazepine. | [IC 50]
PLK1: <500 nM (IC50) |
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