| Identification | Back Directory | [Name]
AAI-101 | [CAS]
1001404-83-6 | [Synonyms]
AAI-101
AAI-101;AAI101
Enmetazobactam
AAI-101, Enmetazobactam
AAI-101; AAI-101; AAI-101, ENMETAZOBACTAM
AAI 101,Bacterial,inhibit,AAI-101,Enmetazobactam,Inhibitor | [Molecular Formula]
C11H14N4O5S | [MDL Number]
MFCD30803316 | [MOL File]
1001404-83-6.mol | [Molecular Weight]
314.318 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C, protect from light, stored under nitrogen | [solubility ]
DMSO:113.3(Max Conc. mg/mL);360.46(Max Conc. mM) | [form ]
A solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens[1][2]. | [in vivo]
In neutropenic animals, cefepime-Enmetazobactam treatment results in reductions in bacterial density of ≥0.5 log10 CFU for 12 of the 20 strains tested and reductions of ≥1 log10 CFU for 6 of these. Increases in bacterial density are for only four strains, three of which have cefepime-Enmetazobactam MICs of ≥64 mg/L, irrespective of the Enmetazobactam concentration[2]. | [storage]
Store at -20°C, protect from light, stored under nitrogen |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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