| Identification | Back Directory | [Name]
ACT 178882 | [CAS]
1007392-69-9 | [Synonyms]
MK-1597
ACT 178882
3-Piperidinecarboxamide, N-[[2-chloro-5-(2-methoxyethyl)phenyl]methyl]-N-cyclopropyl-4-[6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]-3-pyridinyl]-, (3R,4S)- | [Molecular Formula]
C33H38Cl3N3O4 | [MDL Number]
MFCD31544404 | [MOL File]
1007392-69-9.mol | [Molecular Weight]
647.03 |
| Hazard Information | Back Directory | [Uses]
ACT 178882 is a new Renin inhibitor with an IC50 of 1.4 nM. | [References]
[1] Corminboeuf O, et al. Piperidine-based renin inhibitors: upper chain optimization. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6291-6. DOI:10.1016/j.bmcl.2010.08.087
[2] Dingemanse J, et al. Drug-drug interaction study of ACT-178882, a new renin inhibitor, and diltiazem in healthy subjects. Clin Drug Investig. 2013 Mar;33(3):207-13. DOI:10.1007/s40261-013-0056-2 |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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