| Identification | Back Directory | [Name]
N-ACETYL-3-ACETOXY-5-PHENYLPYRROLE | [CAS]
100750-39-8 | [Synonyms]
N-ACETYL-3-ACETOXY-5-PHENYLPYRROLE
(1-acetyl-5-phenylpyrrol-3-yl) acetate
1-Acetyl-5-phenyl-1H-pyrrol-3-ol Acetate
1-[4-(Acetyloxy)-2-phenyl-1H-pyrrol-1-yl]ethanone | [Molecular Formula]
C14H13NO3 | [MDL Number]
MFCD09753637 | [MOL File]
100750-39-8.mol | [Molecular Weight]
243.258 |
| Chemical Properties | Back Directory | [Appearance]
Orange Solid | [Melting point ]
55-57°C | [Boiling point ]
417.6±33.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [solubility ]
Chloroform, Dichloromethane, Methanol | [form ]
Solid | [pka]
-8.35±0.70(Predicted) | [color ]
Orange |
| Hazard Information | Back Directory | [Chemical Properties]
Orange Solid | [Uses]
APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1]. | [References]
[1] Zhi-Ming Xiu, et al. 1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4482-4487. DOI:10.1016/j.bmcl.2017.08.002 |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Carbosynth
|
| Tel: |
+86 512 6260 5585 |
| Website: |
www.carbosynth.com |
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