| Identification | Back Directory | [Name]
Asudemotide | [CAS]
1018833-53-8 | [Synonyms]
Asudemotide
L-Isoleucine, L-α-glutamyl-L-tyrosyl-L-tyrosyl-L-α-glutamyl-L-leucyl-L-phenylalanyl-L-valyl-L-asparaginyl- | [Molecular Formula]
C58H80N10O17 | [MOL File]
1018833-53-8.mol | [Molecular Weight]
1189.31 |
| Chemical Properties | Back Directory | [Boiling point ]
1602.6±65.0 °C(Predicted) | [density ]
1.309±0.06 g/cm3(Predicted) | [pka]
3.35±0.10(Predicted) | [Sequence]
Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile |
| Hazard Information | Back Directory | [Uses]
Asudemotide (S-588410) is a peptide of human DEP domain-containing protein 1A. Asudemotide is an immunostimulant. Asudemotide has a sequence of H-Glu-Tyr-Tyr-Glu-Leu-Phe-Val-Asn-Ile-OH. Asudemotide induces a tumor immune response in esophageal cancer. [1]. | [References]
[1] H Daiko, et al.Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients. Cancer Immunol Immunother. 2020, 69, 11. DOI:10.1007/s00262-020-02619-3 |
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