| Chemical Properties | Back Directory | [Boiling point ]
643.095±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.424±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
7.773±0.10(predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
SQLE-IN-1 (compound 19) is a squalene epoxidase (SQLE) inhibitor. SQLE-IN-1 inhibits the proliferation and migration of Huh7 cells. SQLE-IN-1 inhibits the cell cholesterol generation. SQLE-IN-1 increases the expression of PTEN and inhibits PI3K and AKT[1]. | [References]
[1] Liu, Yayun, et al. Novel squalene epoxidase inhibitor and application thereof in preparation of anti-liver cancer drugs. China, CN116987037. 2023-11-03. |
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