| Identification | Back Directory | [Name]
5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester | [CAS]
1024364-57-5 | [Synonyms]
Tyrosinase-IN-20
5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 3,7-dimethyl-5-phenyl-, ethyl ester | [Molecular Formula]
C17H18N2O2S | [MOL File]
1024364-57-5.mol | [Molecular Weight]
314.4 |
| Chemical Properties | Back Directory | [Melting point ]
242-243 °C(Solv: ethanol (64-17-5); acetone (67-64-1)) | [Boiling point ]
443.2±55.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [pka]
0.65±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Tyrosinase-IN-20 (compound 6a) is a potent inhibitor of Tyrosinase with an IC50 of 28.50 μM[1]. | [References]
[1] Ghasemi N, et al. Thiazolopyrimidine derivatives as novel class of small molecule tyrosinase inhibitor. BMC Chem. 2023 Nov 19;17(1):156. DOI:10.1186/s13065-023-01077-z |
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