| Identification | Back Directory | [Name]
4-Benzofuranol, 7-chloro-2-((4-methoxyphenyl)methyl)-3-methyl-5-propyl - | [CAS]
102612-16-8 | [Synonyms]
224
L656
L-656
L 656
L 656224
7-Chloro-2-[(4-methoxyphenyl)methyl]-3-methyl-5-propyl-4-benzofuranol
4-Benzofuranol, 7-chloro-2-((4-methoxyphenyl)methyl)-3-methyl-5-propyl - | [Molecular Formula]
C20H21ClO3 | [MDL Number]
MFCD28163850 | [MOL File]
102612-16-8.mol | [Molecular Weight]
344.83 |
| Hazard Information | Back Directory | [Description]
L 656224 is a 5-LO inhibitor. | [Uses]
L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells (IC50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase (IC50, 4 x 10-7 M). L-656224 is promising for research of asthma and peripheral analgesic agents[1]. | [References]
[1] Belanger P, et al. L-656,224 (7-chloro-2-[(4-methoxyphenyl)methyl]-3- methyl-5-propyl-4-benzofuranol): a novel, selective, orally active 5-lipoxygenase inhibitor. Can J Physiol Pharmacol. 1987 Dec;65(12):2441-8. DOI:10.1139/y87-387 |
|
|