| Identification | Back Directory | [Name]
1,3-benzodioxol-5-ol, 6-[(2,3-dimethoxyphenyl)-4-morpholinylmethyl]- | [CAS]
102616-64-8 | [Synonyms]
Frataxin-IN-1
1,3-benzodioxol-5-ol, 6-[(2,3-dimethoxyphenyl)-4-morpholinylmethyl]- | [Molecular Formula]
C20H23NO6 | [MDL Number]
MFCD00667275 | [MOL File]
102616-64-8.mol | [Molecular Weight]
373.4 |
| Hazard Information | Back Directory | [Uses]
Frataxin-in-1 (Compound (+)-11) is a Frataxin inhibitor with IC50 value of 45 μM, which can be used in the study of Friedreich's ataxia (FRDA)[1]. | [References]
[1] Lavecchia A, et al. Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays. J Med Chem. 2013 Apr 11;56(7):2861-73. DOI:10.1021/jm3017199 |
|
|