| Identification | Back Directory | [Name]
NEUROPEPTIDE Y (2-36) (PORCINE) | [CAS]
102961-52-4 | [Synonyms]
NPY (2-36) (PORCINE)
Porcine neuropeptide Y(2-36)
NEUROPEPTIDE Y (2-36) (PORCINE)
NEUROPEPTIDE Y (2-36), AMIDE, PORCINE
PSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2
PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-LEU-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2
H-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-LEU-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2
TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-LEU-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2: YPSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2 | [MDL Number]
MFCD00241250 |
| Hazard Information | Back Directory | [Uses]
Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC50 values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders[1]. | [in vivo]
Neuropeptide Y (2-36) (porcine) (1.23 μg/rat; i.c.v.; single) induces food intake in rats[1]. | Animal Model: | Male Sprague-Dawley rats (180-220 g)[1]. | | Dosage: | 1.23 μg/rat (300 pmol/rat) | | Administration: | Intracerebroventricular injection; single | | Result: | Increased food intake to 5.0 g 4 hours later. |
| [References]
[1] Gerald C, et al. A receptor subtype involved in neuropeptide-Y-induced food intake. Nature. 1996 Jul 11;382(6587):168-71. DOI:10.1038/382168a0 |
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