| Identification | Back Directory | [Name]
3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione | [CAS]
103056-35-5 | [Synonyms]
WAY-298516
3-Chloro-4-morpholino-1-phenyl-1H-pyrrole-2,5-dione
3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 3-chloro-4-(4-morpholinyl)-1-phenyl- | [Molecular Formula]
C14H13ClN2O3 | [MOL File]
103056-35-5.mol | [Molecular Weight]
292.72 |
| Hazard Information | Back Directory | [Uses]
RAD51-IN-9 (Compound 3a) is a RAD51 inhibitor that can inhibit the binding of RAD51 to ssDNA with an IC50 of 17.85 μM. RAD51-IN-9 has a LD50 against HEK293 cells of 40.21 μM. RAD51-IN-9 can sensitize cells to Mitomycin C (HY-13316)[1]. | [References]
[1] Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56(1):254-63. DOI:10.1021/jm301565b |
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| Company Name: |
OTAVA chemicals
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| Tel: |
416 305 9979 (Canada) |
| Website: |
www.otavachemicals.com |
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