ChemicalBook--->CAS DataBase List--->1036207-61-0

1036207-61-0

1036207-61-0 Structure

1036207-61-0 Structure
IdentificationBack Directory
[Name]

Tetrapeptide-30
[CAS]

1036207-61-0
[Synonyms]

Tetrapeptide-30
Teterapeptide-30
H-Pro-Lys-Glu-Lys-OH
L-Lysine, L-prolyl-L-lysyl-L-α-glutamyl-
Tetrapeptide-30 (skin lightening peptide)
(S)-6-Amino-2-((S)-2-((S)-6-amino-2-((S)-pyrrolidine-2-carboxamido)hexanamido)-4-carboxybutanamido)hexanoic acid
[EINECS(EC#)]

-0
[Molecular Formula]

C22 H40 N6 O7
[MDL Number]

MFCD32706887
[MOL File]

1036207-61-0.mol
[Molecular Weight]

500.59
Chemical PropertiesBack Directory
[Boiling point ]

931.5±65.0 °C(Predicted)
[density ]

1.256±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C, protect from light, stored under nitrogen
[form ]

Solid
[pka]

3.24±0.10(Predicted)
[color ]

White to off-white
[Cosmetics Ingredients Functions]

SKIN CONDITIONING
SKIN PROTECTING
[InChIKey]

LYHZXMVNRVAAJA-PEFLOIOHNA-N
[SMILES]

[C@@H](CCCCN)(NC([C@H]1NCCC1)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)O)CCCCN |&1:0,8,17,26,r|
Hazard InformationBack Directory
[Description]

Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. It can act as a tyrosinase inhibitor, lightening hyperpigmentation and evening out skin tone by reducing the amount of tyrosinase and inhibiting melanocyte activation.
[Uses]

Tetrapeptide-30 is a skin-brightening peptide consisting of four amino acids. Tetrapeptide-30 can act as a tyrosinase inhibitor, lightening hyperpigmentation and evening out skin tone by reducing the amount of tyrosinase and inhibiting melanocyte activation[1].
[Application]

Light skin freckle, reduce melanin overproduction, reduce melanin deposition, can be added to skin care products, such as skin cream, skin foundation, powder, freckle cream (sunburn, freckles).
[References]

[1] Alessandra Marini, et al. Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects. Exp Dermatol. 2012 Feb;21(2):140-6. DOI:10.1111/j.1600-0625.2011.01415.x
[2] Reinhard H H Neubert, et al. Dermal peptide delivery using enhancer moleculs and colloidal carrier systems. Part II: Tetrapeptide PKEK. Eur J Pharm Biopharm. 2018 Mar;124:28-33. DOI:10.1016/j.ejpb.2017.12.004
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