| Identification | Back Directory | [Name]
Benzaldehyde, 4-(dipropylamino)-3-nitro- | [CAS]
1039855-56-5 | [Synonyms]
ALDH3A1-IN-1
Benzaldehyde, 4-(dipropylamino)-3-nitro- | [Molecular Formula]
C13H18N2O3 | [MOL File]
1039855-56-5.mol | [Molecular Weight]
250.29 |
| Chemical Properties | Back Directory | [Boiling point ]
386.0±37.0 °C(Predicted) | [density ]
1.153±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
-0.09±0.50(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with an IC50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination research with docetaxel[1]. | [IC 50]
ALDH3 | [References]
[1] Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848. DOI:10.1021/acs.jmedchem.1c01367 |
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