| Identification | More | [Name]
Pirenoxine | [CAS]
1043-21-6 | [Synonyms]
1-hydroxy-5-oxo-5h-pyrido[3,2-a]phenoxazine-3-carboxylic acid
PIRENOXINE
1-Hydroxy-5-oxo-5H-pyrido[3,2-]phenoxazine-3-carboxylicacid
Bernetine
catalin
1-Hydroxy-3-carboxy-5H-pyrido[3,2-a]phenoxazin-5-one
1-Hydroxy-5H-pyrido[3,2-a]phenoxazin-5-one-3-carboxylic acid
5H-Pyrido[3,2-a]phenoxazine-3-carboxylic acid, 1-hydroxy-5-oxo-
Catalin K
Catalin【opthalmic remedy】
Kary Uni | [EINECS(EC#)]
213-872-4 | [Molecular Formula]
C16H8N2O5 | [MDL Number]
MFCD00867148 | [Molecular Weight]
308.25 | [MOL File]
1043-21-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
247-248°C | [Boiling point ]
699.7±55.0 °C(Predicted) | [density ]
1.70±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Aqueous Base (Slightly) | [form ]
Solid | [pka]
2.63±0.20(Predicted) | [color ]
Very Dark Red to Very Dark Brown | [InChI]
InChI=1S/C16H8N2O5/c19-9-5-8(16(21)22)18-14-10(20)6-12-15(13(9)14)17-7-3-1-2-4-11(7)23-12/h1-6H,(H,18,19)(H,21,22) | [InChIKey]
OKPNYGAWTYOBFZ-UHFFFAOYSA-N | [SMILES]
C12=C(O)C=C(C(O)=O)N=C1C(=O)C=C1C2=NC2=C(C=CC=C2)O1 | [CAS DataBase Reference]
1043-21-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
antiviral | [Definition]
ChEBI: Pirenoxine is an organic molecular entity. | [in vivo]
Pirenoxine (0.005% pirenoxine; eye drop) suppresses lens hardening and prevents the progression of presbyopia[2]. | Animal Model: | Six-week-old male Sprague-Dawley rats[2] | | Dosage: | 0.005% pirenoxine | | Administration: | Eye drop | | Result: | Significantly suppressed lens hardening. |
|
|
|