| Identification | Back Directory | [Name]
Sch 34826 | [CAS]
105262-04-2 | [Synonyms]
Sch 34826
N-[N-[2-[(2,2-Dimethyl-1,3-dioxolan-4-yl)methoxy]-2-oxo-1-(phenylmethyl)ethyl]-L-phenylalanyl]-β-alanine | [Molecular Formula]
C27H34N2O7 | [MOL File]
105262-04-2.mol | [Molecular Weight]
498.568 |
| Hazard Information | Back Directory | [Uses]
SCH-34826 is an orally active neutral metalloendopeptidase (NEP) inhibitor that inhibits NEP and reduces the degradation of ANF, thereby enhancing its antihypertensive and diuretic effects. SCH-34826 can be used in the research of cardiovascular and renal diseases[1]. | [References]
[1] Sybertz E J, et al. Atrial natriuretic factor-potentiating and antihypertensive activity of SCH 34826. An orally active neutral metalloendopeptidase inhibitor[J]. Hypertension, 1990, 15(2): 152-161. DOI:10.1161/01.hyp.15.2.152 |
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