| Identification | Back Directory | [Name]
Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester | [CAS]
105380-95-8 | [Synonyms]
Diphosphatidylglycerol (16:0)
Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester | [Molecular Formula]
C73H142O17P2 | [MOL File]
105380-95-8.mol | [Molecular Weight]
1353.85 |
| Chemical Properties | Back Directory | [Boiling point ]
1091.866±75.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.030±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
Chloroform: Soluble | [pka]
0.999±0.50(predicted) |
| Hazard Information | Back Directory | [Uses]
16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads[1]. | [References]
[1] Junxiang Zhou, et al. A feedback loop engaging propionate catabolism intermediates controls mitochondrial morphology. Nat Cell Biol. 2022 Apr;24(4):526-537. DOI:10.1038/s41556-022-00883-2 |
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