| Identification | More | [Name]
Tropisetron hydrochloride | [CAS]
105826-92-4 | [Synonyms]
(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE
3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE
TROPISETRON HCL
TROPISETRON HYDROCHLORIDE
TROPISETRON HYDROCHLORIDE 98.5-101.5%
TropisetronHcl/Mesylate
1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1)
1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride
Novaban
SDZ-ICS 930
3-Tropanylindole-3-carboxylate monohydrochloride, ICS-205,930, Navoban, 1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride
Tropisetron monohydrochloride | [EINECS(EC#)]
630-417-9 | [Molecular Formula]
C17H21ClN2O2 | [MDL Number]
MFCD02313825 | [Molecular Weight]
320.81 | [MOL File]
105826-92-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White to Off-White Crystalline Solid | [Melting point ]
283-285°C | [RTECS ]
NL6012520 | [storage temp. ]
2-8°C | [solubility ]
H2O: >10mg/mL | [form ]
solid | [color ]
White to Light yellow | [Water Solubility ]
Soluble in water | [Usage]
Specific serotonin (5-HT3) receptor antagonist. Antiemetic. | [Merck ]
14,9783 | [InChI]
InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,15H,6-9H2,1H3;1H/t11-,12+,13?,15?; | [InChIKey]
ZAOQBEAHJFSJLY-NBVCILBMNA-N | [SMILES]
C12C=CC=CC=1N=CC2C(=O)OC1C[C@]2([H])N(C)[C@@]([H])(CC2)C1.Cl |&1:14,18,r| | [CAS DataBase Reference]
105826-92-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301 | [Precautionary statements ]
P264-P270-P301+P310a-P321-P405-P501a | [RIDADR ]
2811 | [WGK Germany ]
3 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29399990 | [Storage Class]
11 - Combustible Solids | [Toxicity]
mouse,LD50,intravenous,37900ug/kg (37.9mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2445, 1998. |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Crystalline Solid | [Uses]
A selective 5-HT3 serotonin receptor antagonist | [Uses]
Specific serotonin (5-HT3) receptor antagonist. Antiemetic. | [Definition]
ChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride. | [Biological Activity]
Potent, orally active 5-HT 3 receptor antagonist. Antiemetic. | [Biochem/physiol Actions]
Tropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment. | [storage]
Room temperature (desiccate) |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|