| Identification | More | [Name]
Rufloxacin hydrochloride | [CAS]
106017-08-7 | [Synonyms]
RUFLOXACIN HCL
RUFLOXACIN HYDROCHLORIDE
7h-pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylicacid,2,3-dihydro-9-fluoro-1
mf-934
RUFLOXACINHYDROCHLORIDE(SUBJECTTOPATENTFREE)
2,3-Dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride | [Molecular Formula]
C17H19ClFN3O3S | [MDL Number]
MFCD00912283 | [Molecular Weight]
399.87 | [MOL File]
106017-08-7.mol |
| Hazard Information | Back Directory | [Description]
Rufloxacin hydrochloride is another fluoroquinolone orally active antibacterial
structurally and mechanistically related to temafloxacin and tosufloxacin. It is useful
for the treatment of respiratory and urinary tract infections and also chronic bacterial
prostatitis. Good tissue penetration with long acting activity has been reported. | [Originator]
Mediolanum (Italy) | [Uses]
Rufloxacin Hydrochloride inhibits human organic cation transporter 1 (hoCT1) (SLC22A1) but not hOCT2 (SLC22A2), and hOCT3 (SLC22A3) expressed in human embryonic kidney cell. | [Brand name]
Qari; Monos |
| Safety Data | Back Directory | [Toxicity]
LD50 in rats, mice (mg/kg): 285, 224 i.v.; LD50 in rabbits, male, female rats (mg/kg): 660, 631, 501 orally (Cecchetti) |
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