| Identification | Back Directory | [Name]
(1,5-dihydroxy-2-oxopyrrolidin-3-yl)phosphonic acid | [CAS]
107729-45-3 | [Synonyms]
SF 2312(SF2312)
(1,5-dihydroxy-2-oxopyrrolidin-3-yl)phosphonic acid
Phosphonic acid, P-(1,5-dihydroxy-2-oxo-3-pyrrolidinyl)- | [Molecular Formula]
C4H8NO6P | [MOL File]
107729-45-3.mol | [Molecular Weight]
197.08 |
| Chemical Properties | Back Directory | [Boiling point ]
588.1±60.0 °C(Predicted) | [density ]
2.01±0.1 g/cm3(Predicted) | [form ]
Oil | [pka]
1.25±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions[1]. | [References]
[1] Paul G Leonard, et al. SF2312 is a natural phosphonate inhibitor of enolase. Nat Chem Biol. 2016 Dec;12(12):1053-1058. DOI:10.1038/nchembio.2195 |
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hangzhoubaiyibiolog
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15658107580 |
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www.chemicalbook.com/ShowSupplierProductsList1389215/0_EN.htm |
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Biorbyt Ltd.
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http://www.biorbyt.com |
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