| Identification | Back Directory | [Name]
16-OXOKAHWEOL | [CAS]
108664-99-9 | [Synonyms]
16-OXOKAHWEOL
OXOKAHWEOL, 16-
OXOKAHWEOL, 16-(RG)
OXOCAFESTOL, 16-(RG)
16-Oxokahweol >=98% (HPLC)
5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7(6H)-one, 3b,4,5,8,9,10,10a,10b-octahydro-10b-methyl-, (3bS,5aS,8R,10aR,10bS)- | [Molecular Formula]
C19H22O2 | [MDL Number]
MFCD00214109 | [MOL File]
108664-99-9.mol | [Molecular Weight]
282.38 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Water: soluble | [form ]
A solid | [Water Solubility ]
Water: soluble | [InChI]
1S/C19H22O2/c1-18-7-5-16-13(6-9-21-16)14(18)4-8-19-10-12(15(20)11-19)2-3-17(18)19/h5-7,9,12,14,17H,2-4,8,10-11H2,1H3/t12-,14+,17-,18+,19+/m0/s1 | [InChIKey]
ZUHATORLUREVSD-OXQYBPPISA-N | [SMILES]
CC12C=Cc3occc3C1CCC45CC(CCC24)C(=O)C5 |
| Hazard Information | Back Directory | [Description]
16-Oxokahweol is a synthetic diterpene and derivative of kahweol . It increases cytosolic glutathione S-transferase (GST) activity and acid-soluble sulfhydryl levels in mouse liver and small bowel mucosa when administered at a dose of 10 μmol/animal once per day for three days. | [Uses]
16-Oxokahweol, a Kahweol (HY-N6258) derivative, is a glutathione S-transferase inducer[1]. | [storage]
Store at -20°C | [References]
[1] L K Lam, et al. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice. J Med Chem. 1987 Aug;30(8):1399-403. DOI:10.1021/jm00391a022 |
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