| Identification | Back Directory | [Name]
11(R)-HEPE | [CAS]
109430-11-7 | [Synonyms]
11(R)-HEPE
IDEHSDHMEMMYIR-DJWFCICMSA-N
11R-Hydroxy-5Z,8Z,12E,14Z,17Z-eicosadienoic acid
11R-HYDROXY-5Z,8Z,12E,14Z,17Z-EICOSAPENTAENOIC ACID
5,8,12,14,17-Eicosapentaenoic acid, 11-hydroxy-, (5Z,8Z,11R,12E,14Z,17Z)- | [Molecular Formula]
C20H30O3 | [MDL Number]
MFCD00216117 | [MOL File]
109430-11-7.mol | [Molecular Weight]
318.45 |
| Chemical Properties | Back Directory | [Boiling point ]
488.0±45.0 °C(Predicted) | [density ]
0.997±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | [pka]
4.75±0.10(Predicted) | [InChIKey]
IDEHSDHMEMMYIR-DJWFCICMSA-N | [SMILES]
C(O)(=O)CCC/C=C\C/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CC |
| Hazard Information | Back Directory | [Description]
11(R)-HEPE is produced by the oxidation of EPA by 11(R)-LO. This enzymatic activity and the resulting 11(R)-hydroxy acid have been isolated from the sea urchin S. purpuratus. | [Uses]
11(R)-HEPE is a monohydroxy fatty acid derived from EPA (eicosapentaenoic acid)[1]. | [Definition]
ChEBI: 11(R)-HEPE is an 11-HEPE that consists of (5Z,8Z,12E,14Z,17Z)-icosapentaenoic acid in which the hydroxy group is located at the 11R-position. It has a role as a human xenobiotic metabolite, an anti-inflammatory agent and an algal metabolite. It is a conjugate acid of an 11(R)-HEPE(1-). | [References]
[1] Di Marzo V, et al. Polyunsaturated-fatty-acid oxidation in Hydra: regioselectivity, substrate-dependent enantioselectivity and possible biological role. Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):501-7. DOI:10.1042/bj3000501 |
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Alfa Chemistry
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1-516-6625404 |
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https://www.alfa-chemistry.com |
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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www.enzo.com |
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