| Identification | Back Directory | [Name]
(R)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione | [CAS]
110351-91-2 | [Synonyms]
(R)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
(4R)-4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy-, (R)- (9CI)
5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano<3',4'-f>Δ6,8-tetrahydroindolizine | [Molecular Formula]
C13H13NO5 | [MDL Number]
MFCD29045786 | [MOL File]
110351-91-2.mol | [Molecular Weight]
263.25 |
| Chemical Properties | Back Directory | [Melting point ]
169-170 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
666.6±55.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
11.20±0.20(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2]. | [IC 50]
Camptothecins |
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Cool Pharm, Ltd
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021-58581007 18019463053 |
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http://www.coolpharm.com.cn |
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