Identification | Back Directory | [Name]
Uridine,3'-azido-2',3'-dideoxy-5-hydroxy- | [CAS]
111495-90-0 | [Synonyms]
Uridine,3'-azido-2',3'-dideoxy-5-hydroxy- 3’-Azido-2’,3’-dideoxy-5-hydroxyuridine, antiviral agent | [Molecular Formula]
C9H11N5O5 | [MOL File]
111495-90-0.mol | [Molecular Weight]
269.22 |
Hazard Information | Back Directory | [Uses]
3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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