ChemicalBook--->CAS DataBase List--->111495-90-0

111495-90-0

111495-90-0 Structure

111495-90-0 Structure
IdentificationBack Directory
[Name]

Uridine,3'-azido-2',3'-dideoxy-5-hydroxy-
[CAS]

111495-90-0
[Synonyms]

Uridine,3'-azido-2',3'-dideoxy-5-hydroxy-
3’-Azido-2’,3’-dideoxy-5-hydroxyuridine, antiviral agent
[Molecular Formula]

C9H11N5O5
[MOL File]

111495-90-0.mol
[Molecular Weight]

269.22
Hazard InformationBack Directory
[Uses]

3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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