| Identification | Back Directory | [Name]
Uridine, 4',5'-didehydro-5'-deoxy- | [CAS]
14365-63-0 | [Synonyms]
4',5'-Didehydro-5'-deoxyuridine
Uridine, 4',5'-didehydro-5'-deoxy-
1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil
1-((2R,3R,4S)-3,4-dihydroxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C9H10N2O5 | [MDL Number]
MFCD23160105 | [MOL File]
14365-63-0.mol | [Molecular Weight]
226.19 |
| Chemical Properties | Back Directory | [Melting point ]
169-170 °C(Solv: acetone (67-64-1)) | [density ]
1.61±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.34±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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