| Identification | Back Directory | [Name]
2-(2-(pyridin-2-yl)disulfanyl)ethanol | [CAS]
111625-28-6 | [Synonyms]
2-(2-Pyridinyldithio)ethanol
Ethanol, 2-(2-pyridinyldithio)-
2-(2-Pyridinyldisulfanyl)ethanol
(2-pyridyldithio)-PEG1-hydrazine
2-(Pyridin-2-yldisulfanyl)ethanol
2-(pyridin-2-yldisulfanyl)ethan-1-ol
2-(2-(pyridin-2-yl)disulfanyl)ethanol
S-2-pyridyl-S'-2-hydroxyethyl disulfide | [EINECS(EC#)]
631-203-8 | [Molecular Formula]
C7H9NOS2 | [MOL File]
111625-28-6.mol | [Molecular Weight]
187.28 |
| Chemical Properties | Back Directory | [Boiling point ]
323.3±38.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [form ]
Solid-Liquid Mixture | [pka]
14.22±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Disulfide Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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