| Identification | Back Directory | [Name]
L-(-)-VESAMICOL HYDROCHLORIDE | [CAS]
112709-59-8 | [Synonyms]
L(-)-VESAMICOL HCL
1r-trans-cyclohexano
L-(-)-VESAMICOL HYDROCHLORIDE
(1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol
Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, (1R,2R)-
L-(-)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride | [Molecular Formula]
C17H25NO | [MDL Number]
MFCD00069371 | [MOL File]
112709-59-8.mol | [Molecular Weight]
259.39 |
| Chemical Properties | Back Directory | [Melting point ]
238.5-240.0 °C | [Boiling point ]
393.5±42.0 °C(Predicted) | [density ]
1.086±0.06 g/cm3(Predicted) | [form ]
solid | [pka]
15.16±0.40(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
(-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study[1]. | [Definition]
ChEBI: (1R,2R)-2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines. | [References]
[1] Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116. DOI:10.1113/jphysiol.1991.sp018868 |
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