| Identification | Back Directory | [Name]
BOC-VAL-ARG-AMC HCL | [CAS]
113865-96-6 | [Synonyms]
BOC-VR-AMC
Boc-Val-Arg-AMC
BOC-VAL-ARG-AMC HCL
L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- (9CI)
tert-butyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate | [Molecular Formula]
C26H38N6O6 | [MDL Number]
MFCD08458563 | [MOL File]
113865-96-6.mol | [Molecular Weight]
530.62 |
| Hazard Information | Back Directory | [Uses]
Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples[1]. | [References]
[1] Gravemann U, et al. Thrombin generation capacity of methylene blue-treated plasma prepared by the Theraflex MB plasma system[J]. Transfusion Medicine and Hemotherapy, 2009, 36(2): 122-127. DOI:10.1159/000202413 |
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